MIS-A Multisystem Inflammatory Syndrome in Adults

MIS-A Multisystem Inflammatory Syndrome in Adults

The extent to which the body is being affected by the coronavirus-2 is being realized from time to time. Around the world, many cases of MIS-C is Multisystem Inflammatory Syndrome in children are reported after contracting COVID-19 and now this disease is also found in adults known as MIS-A.

A Chest Specialist Dr. Milan Modi and an infectious disease specialist Dr. Pratik Savaj diagnosed the MIS-A patients in the Surat city of Gujarat, India. About 8 to 9 such cases have been reported in the city. Today we will discuss this disease in short.

What is MIS-A?

The full name of MIS-A is Multi-System Inflammatory Syndrome in Adults with COVID-19, which can also be called Post COVID-19 Syndrome.

This syndrome is reported in many children but now it is also found in adults affecting multiple systems and various organs of the body.

What causes Multisystem inflammatory syndrome?

The disease is associated with SARS-COV-2 infection. In most cases, the disease occurs within a period of 6 to 8 weeks after the coronavirus-2 infection. So it can be said that those who have been infected with corona, can be affected by MIS-A.

What are the symptoms of MIS-A?

It is a rare complication of COVID-19 but affected persons are at higher risk. Patients have different symptoms and common are fever, joints pain, rashes on the skin, and lymph nodes in the neck area. Multiple systems and organs are also affected causing inflammation of the liver, kidney, edema of the hands, and feet. Most of the patients have cardiac involvement also and have an increase in CRP levels with other inflammatory markers like D-dimer, interleukin-6, and ferritin.

How is the diagnosis of MIS-A is done?

The affected patient is evaluated for SARS-COV-2 infection. RTPCR, Rapid antigen, antibody, and other necessary tests are done for COVID-19.

Differential diagnoses of Urinary tract infections, malaria, dengue, and especially chikungunya are done and tests are performed accordingly. If these tests are negative, then MIS-A is treated.

How is MIS-A is treated?

After diagnosis and evaluation of MIS-A, it is treated. Treatment is done according to the severity of the disease.

Patients are also given pain medication (NSAIDs), and critically ill patients are being given aspirin or IVIG. Severely ill patients may also require intensive care with mechanical circulatory support and a mechanical ventilator.

Timely diagnosis and treatment can lead to good results. If the diagnosis is delayed, it can cause fluid collection around layers of the heart, can damage the lungs, lowers blood pressure, may have to be kept on a ventilator, and in some cases, even Multi-Organ Disease (MOD) can occur.

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